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1

EXPRESSION OF CYCLIN-DEPENDENT KINASE INHIBITOR p21WAF1/CIP1 IN NON-NEOPLASTIC MUCOSA AND NEOPLASIA OF THE STOMACH: RELATIONSHIP WITH p53 STATUS AND PROLIFERATIVE ACTIVITY

YASUI, WATARU, AKAMA, YOSHIHIKO, KUNIYASU, HIROKI, YOKOZAKI, HIROSHI, SEMBA, SHUHO, SHIMAMOTO, FUMIO, TAHARA, EIICHI

Journal:

The Journal of Pathology

Year:

1996

Language:

english

File:

PDF, 893 KB

english, 1996

2

Microsatellite instability in precancerous lesions and adenocarcinomas of the stomach

Shuho Semba, Hiroshi Yokozaki, Soichiro Yamamoto, Wataru Yasui, Eiichi Tahara

Journal:

Year:

1996

Language:

english

File:

PDF, 749 KB

english, 1996

3

Frequent nuclear accumulation of β-catenin in pituitary adenoma

Shuho Semba, Shuang-Yin Han, Hidetoshi Ikeda, Akira Horii

Journal:

Year:

2001

Language:

english

File:

PDF, 269 KB

english, 2001

4

Phosphorylation of Akt/PKB is required for suppression of cancer cell apoptosis and tumor progression in human colorectal carcinoma

Nanami Itoh, Shuho Semba, Masafumi Ito, Hiroaki Takeda, Sumio Kawata, Mitsunori Yamakawa

Journal:

Year:

2002

Language:

english

File:

PDF, 683 KB

english, 2002

5

BRAF mutation associated with dysregulation of apoptosis in human colorectal neoplasms

Nobunao Ikehara, Shuho Semba, Masanori Sakashita, Nobuo Aoyama, Masato Kasuga, Hiroshi Yokozaki

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 598 KB

english, 2005

6

Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity

Joshua P. Cantor, Dimitrios Iliopoulos, Atul S. Rao, Teresa Druck, Shuho Semba, Shuang-Yin Han, Kelly A. McCorkell, Thiru V. Lakshman, Joshua E. Collins, Phyllis Wachsberger, Joseph S. Friedberg, Kay

Journal:

International Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 545 KB

english, 2007

7

Down-modulation of keratin 8 phosphorylation levels by PRL-3 contributes to colorectal carcinoma progression

Eri Mizuuchi, Shuho Semba, Yoshinori Kodama, Hiroshi Yokozaki

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 2.22 MB

english, 2009

8

Relationship ofBRAFmutation, morphology, and apoptosis in early colorectal cancer

Shiei Yoshida, Nobunao Ikehara, Nobuo Aoyama, Daisuke Shirasaka, Masanori Sakashita, Shuho Semba, Tadateru Hasuo, Ikuya Miki, Yoshinori Morita, Takao Tamura, Takeshi Azuma, Hiroshi Yokozaki, Masato Ka

Journal:

International Journal of Colorectal Disease

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

9

Loss of WW domain-containing oxidoreductase expression in the progression and development of gastric carcinoma: clinical and histopathologic correlations

Naoko Maeda, Shuho Semba, Shunji Nakayama, Kazuyoshi Yanagihara, Hiroshi Yokozaki

Journal:

Virchows Archiv

Year:

2010

Language:

english

File:

PDF, 862 KB

english, 2010

10

BRAF/K-rasmutation, microsatellite instability, and promoter hypermethylation ofhMLH1/MGMTin human gastric carcinomas

Ming Wu, Shuho Semba, Naohide Oue, Nobunao Ikehara, Wataru Yasui, Hiroshi Yokozaki

Journal:

Year:

2004

Language:

english

File:

PDF, 219 KB

english, 2004

11

Reduced Expression of Cyclin–dependent Kinase Inhibitor p27Kipl Is Associated with Advanced Stage and Invasiveness of Gastric Carcinomas

Wataru Yasui, Yasusei Kudo, Shuho Semba, Hiroshi Yokozaki, Eüchi Tahara

Journal:

Year:

1997

File:

PDF, 366 KB

1997

12

Expression of the DMBT1 Gene Is Frequently Suppressed in Human Lung Cancer

Hiroaki Takeshita, Masami Sato, Hiromi O. Shiwaku, Shuho Semba, Akira Sakurada, Masato Hoshi, Yutaka Hayashi, Yutaka Tagawa, Hiroyoshi Ayabe, Akira Horii

Journal:

Year:

1999

Language:

english

File:

PDF, 230 KB

english, 1999

13

Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer

Yasuko Matsukawa, Shuho Semba, Hirotaka Kato, Akihiko Ito, Kazuyoshi Yanagihara, Hiroshi Yokozaki

Journal:

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

14

Gastric and intestinal claudin expression at the invasive front of gastric carcinoma

Yoshiko Matsuda, Shuho Semba, Junya Ueda, Takeichi Fuku, Tadateru Hasuo, Hideki Chiba, Norimasa Sawada, Yoshikazu Kuroda, Hiroshi Yokozaki

Journal:

Year:

2007

Language:

english

File:

PDF, 279 KB

english, 2007

15

Restoration of fragile histidine triad expression restores Chk2 activity in response to ionizing radiation in oral squamous cell carcinoma cells

Hirokazu Yutori, Shuho Semba, Takahide Komori, Hiroshi Yokozaki

Journal:

Year:

2008

Language:

english

File:

PDF, 545 KB

english, 2008

16

Role of the WWOX gene, encompassing fragile region FRA16D, in suppression of pancreatic carcinoma cells

Shunji Nakayama, Shuho Semba, Naoko Maeda, Rami I. Aqeilan, Kay Huebner, Hiroshi Yokozaki

Journal:

Year:

2008

Language:

english

File:

PDF, 339 KB

english, 2008

17

Alternative lengthening of telomeres frequently occurs in mismatch repair system-deficient gastric carcinoma

Yasuhiro Omori, Fumihito Nakayama, Dong Li, Kiyonori Kanemitsu, Shuho Semba, Akihiko Ito, Hiroshi Yokozaki

Journal:

Year:

2009

Language:

english

File:

PDF, 412 KB

english, 2009

18

Requirement of phosphatase of regenerating liver-3 for the nucleolar localization of nucleolin during the progression of colorectal carcinoma

Shuho Semba, Eri Mizuuchi, Hiroshi Yokozaki

Journal:

Year:

2010

Language:

english

File:

PDF, 912 KB

english, 2010

19

SUPERFICIALLY ELEVATED-TYPE SERRATED HYPERPLASTIC LESION OF THE STOMACH WITH MINUTE ADENOCARCINOMA

Tadateru Hasuo, Shuho Semba, Shinya Satake, Daisuke Shirasaka, Nobuo Aoyama, Hiroshi Yokozaki

Journal:

Digestive Endoscopy

Year:

2009

Language:

english

File:

PDF, 676 KB

english, 2009

20

Nuclear accumulation of β-catenin in human endocrine tumors: Association with Ki-67 (MIB-1) proliferative activity

Shuho Semba, Ryoko Kusumi, Takuya Moriya, Hironobu Sasano

Journal:

Endocrine Pathology

Year:

2000

Language:

english

File:

PDF, 241 KB

english, 2000

21

The cadherin-catenin superfamily in endocrine tumors

Shuho Semba, Mitsunori Yamakawa, Hironobu Sasano

Journal:

Endocrine Pathology

Year:

2001

Language:

english

File:

PDF, 192 KB

english, 2001

22

Minute invasive ductal carcinoma of the residual pancreas after distal pancreatectomy for intraductal papillary-mucinous tumor

Toshiyuki Moriya, Wataru Kimura, Fumiaki Sakurai, Shuho Semba, Koichiro Ozawa, Ichiro Hirai, Akira Fuse

Journal:

Journal of Gastrointestinal Cancer

Year:

2002

Language:

english

File:

PDF, 387 KB

english, 2002

23

Biological similarities and differences between pancreatic intraepithelial neoplasias and intraductal papillary mucinous neoplasms

Toshiyuki Moriya, Wataru Kimura, Shuho Semba, Fumiaki Sakurai, Ichiro Hirai, Jinfeng Ma, Akira Fuse, Kunihiko Maeda, Mitsunori Yamakawa

Journal:

Journal of Gastrointestinal Cancer

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

24

An autopsy case of ovarian hyperstimulation syndrome with massive pulmonary edema and pleural effusion

Shuho Semba, Takuya Moriya, Emile M Youssef, Hironobu Sasano

Journal:

Pathology International

Year:

2000

Language:

english

File:

PDF, 617 KB

english, 2000

25

Expression of p21WAF1/CIP1 in colorectal adenomas and adenocarcinomas and its correlation with p53 protein expression

Wataru Yasd, Yoshihiko Akama, Hiroshi Yokozaki, Shuho Semba, Yasusei Kudo, Fumio Shimamoto, Eiichi Tahara

Journal:

Pathology International

Year:

1997

Language:

english

File:

PDF, 1.40 MB

english, 1997

26

Molecular pathological subclassification of mucinous adenocarcinoma of the colorectum

Dong Li, Shuho Semba, Ming Wu, Hiroshi Yokozaki

Journal:

Pathology International

Year:

2005

Language:

english

File:

PDF, 549 KB

english, 2005

27

Increased wild-type p53-induced phosphatase 1 (Wip1 or PPM1D) expression correlated with downregulation of checkpoint kinase 2 in human gastric carcinoma

Takeichi Fuku, Shuho Semba, Hirokazu Yutori, Hiroshi Yokozaki

Journal:

Pathology International

Year:

2007

Language:

english

File:

PDF, 457 KB

english, 2007

28

Prognostic significance of intestinal claudins in high-risk synchronous and metachronous multiple gastric epithelial neoplasias after initial endoscopic submucosal dissection

Shuho Semba, Tadateru Hasuo, Shinya Satake, Fumihito Nakayama, Hiroshi Yokozaki

Journal:

Pathology International

Year:

2008

Language:

english

File:

PDF, 476 KB

english, 2008

29

Autopsy case of the neonatal form of carnitine palmitoyltransferase-II deficiency triggered by a novel disease-causing mutation del1737C

Shuho Semba, Hidehiro Yasujima, Tomoko Takano, Hiroshi Yokozaki

Journal:

Pathology International

Year:

2008

Language:

english

File:

PDF, 455 KB

english, 2008

30

Cdx2 transcription factor regulates claudin-3 and claudin-4 expression during intestinal differentiation of gastric carcinoma

Shinya Satake, Shuho Semba, Yoshiko Matsuda, Yu Usami, Hideki Chiba, Norimasa Sawada, Masato Kasuga, Hiroshi Yokozaki

Journal:

Pathology International

Year:

2008

Language:

english

File:

PDF, 492 KB

english, 2008

31

Analysis of gene expression induced by diethylstilbestrol (DES) in human primitive Müllerian duct cells using microarray

Yasuhiro Miki, Takashi Suzuki, Chika Tazawa, Masato Ishizuka, Shuho Semba, Itsuo Gorai, Hironobu Sasano

Journal:

Year:

2005

Language:

english

File:

PDF, 353 KB

english, 2005

32

Phosphatase activity of nuclear PTEN is required for CDX2-mediated intestinal differentiation of gastric carcinoma

Shuho Semba, Shinya Satake, Mai Matsushita, Hiroshi Yokozaki

Journal:

Year:

2009

Language:

english

File:

PDF, 429 KB

english, 2009

33

Expression of cyclin E in colorectal adenomas and adenocarcinomas: correlation with expression of Ki-67 antigen and p53 protein

Yasui, Wataru, Kuniyasu, Hiroki, Yokozaki, Hiroshi, Semba, Shuho, Tahara, Eicchi, Shimamoto, Fumio

Journal:

Virchows Archiv

Year:

1996

Language:

english

File:

PDF, 1.72 MB

english, 1996

34

Hypoxia Induces Tumor Aggressiveness and the Expansion of CD133-Positive Cells in a Hypoxia-Inducible Factor-1α-Dependent Manner in Pancreatic Cancer Cells

Hashimoto, Okito, Shimizu, Kazuya, Semba, Shuho, Chiba, Sachie, Ku, Yonson, Yokozaki, Hiroshi, Hori, Yuichi

Journal:

Year:

2011

Language:

english

File:

PDF, 1005 KB

english, 2011

35

Mesenchymal Stem Cells Provide an Advantageous Tumor Microenvironment for the Restoration of Cancer Stem Cells

Nishimura, Kanako, Semba, Shuho, Aoyagi, Kazuhiko, Sasaki, Hiroki, Yokozaki, Hiroshi

Journal:

Year:

2012

Language:

english

File:

PDF, 2.91 MB

english, 2012

36

Negative Regulation of the Tight Junction Protein Tricellulin by Snail-Induced Epithelial-Mesenchymal Transition in Gastric Carcinoma Cells

Masuda, Risayo, Semba, Shuho, Mizuuchi, Eri, Yanagihara, Kazuyoshi, Yokozaki, Hiroshi

Journal:

Year:

2010

Language:

english

File:

PDF, 678 KB

english, 2010

37

Tumor associated macrophage expressing CD204 is associated with tumor aggressiveness of esophageal squamous cell carcinoma

Shigeoka, Manabu, Urakawa, Naoki, Nakamura, Tetsu, Nishio, Mari, Watajima, Taketo, Kuroda, Daisuke, Komori, Takahide, Kakeji, Yoshihiro, Semba, Shuho, Yokozaki, Hiroshi

Journal:

Year:

2013

Language:

english

File:

PDF, 1.29 MB

english, 2013

38

Jejunal tubulovillous adenocarcinoma in adenoma presenting with entero-enteric intussusception

Nobuhiro Takeuchi, Shuho Semba, Kazuyoshi Naba…

Journal:

Clinical Journal of Gastroenterology

Year:

2013

Language:

english

File:

PDF, 558 KB

english, 2013

39

Second trimester fetal death caused by varicella-zoster virus infection

Tanimura, Kenji, Kojima, Nobue, Yamazaki, Takashi, Semba, Shuho, Yokozaki, Hiroshi, Yamada, Hideto

Journal:

Journal of Medical Virology

Year:

2013

Language:

english

File:

PDF, 857 KB

english, 2013

40

Sorting Nexin 2 (SNX2)

Kanzawa, Maki, Hara, Shigeo, Semba, Shuho, Yokozaki, Hiroshi, Hirokawa, Mitsuyoshi, Itoh, Tomoo

Journal:

Applied Immunohistochemistry & Molecular Morphology

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

41

Biological significance of tumor budding at the invasive front of human colorectal carcinoma cells

Journal:

International Journal of Oncology

Year:

2012

Language:

english

File:

PDF, 735 KB

english, 2012

42

WNT5A is a Key Regulator of the Epithelial-Mesenchymal Transition and Cancer Stem Cell Properties in Human Gastric Carcinoma Cells

Kanzawa, Maki, Semba, Shuho, Hara, Shigeo, Itoh, Tomoo, Yokozaki, Hiroshi

Journal:

Year:

2013

Language:

english

File:

PDF, 461 KB

english, 2013

43

Significance of Akt Phosphorylation on Tumor Growth and Vascular Endothelial Growth Factor Expression in Human Gastric Carcinoma

Kobayashi, Iwao, Semba, Shuho, Matsuda, Yoshiko, Kuroda, Yoshikazu, Yokozaki, Hiroshi

Journal:

Year:

2006

Language:

english

File:

PDF, 642 KB

english, 2006

44

Expression of PRL-3 Phosphatase in Human Gastric Carcinomas: Close Correlation with Invasion and Metastasis

Miskad, Upik Anderiani, Semba, Shuho, Kato, Hirotaka, Yokozaki, Hiroshi

Journal:

Year:

2004

Language:

english

File:

PDF, 1.52 MB

english, 2004

45

Molecular Pathological Analysis of Mucinous Adenocarcinomas of the Stomach

Wu, Ming, Semba, Shuho, Li, Dong, Yokozaki, Hiroshi

Journal:

Year:

2004

Language:

english

File:

PDF, 989 KB

english, 2004

46

Heterogeneous Expression of Claudin-4 in Human Colorectal Cancer: Decreased Claudin-4 Expression at the Invasive Front Correlates Cancer Invasion and Metastasis

Ueda, Junya, Semba, Shuho, Chiba, Hideki, Sawada, Norimasa, Seo, Yasushi, Kasuga, Masato, Yokozaki, Hiroshi

Journal:

Year:

2007

Language:

english

File:

PDF, 405 KB

english, 2007

47

Hypermethylation-Modulated Downregulation of Claudin-7 Expression Promotes the Progression of Colorectal Carcinoma

Nakayama, Fumihito, Semba, Shuho, Usami, Yu, Chiba, Hideki, Sawada, Norimasa, Yokozaki, Hiroshi

Journal:

Year:

2008

Language:

english

File:

PDF, 509 KB

english, 2008

48

Constitutive Suppression of PRL-3 Inhibits Invasion and Proliferation of Gastric Cancer Cell in vitro and in vivo

Matsukawa, Yasuko, Semba, Shuho, Kato, Hirotaka, Koma, Yu-ichiro, Yanagihara, Kazuyoshi, Yokozaki, Hiroshi

Journal:

Year:

2010

Language:

english

File:

PDF, 402 KB

english, 2010

49

Phosphorylated Akt/PKB Controls Cell Growth and Apoptosis in Intraductal Papillary–Mucinous Tumor and Invasive Ductal Adenocarcinoma of the Pancreas

Semba, Shuho, Moriya, Toshiyuki, Kimura, Wataru, Yamakawa, Mitsunori

Journal:

Year:

2003

Language:

english

File:

PDF, 634 KB

english, 2003

50

Prognostic significance of classified extramural tumor deposits and extracapsular lymph node invasion in T3–4 colorectal cancer: a retrospective single-center study

Yamano, Tomoki, Semba, Shuho, Noda, Masafumi, Yoshimura, Mie, Kobayashi, Masayoshi, Hamanaka, Michiko, Beppu, Naohito, Yano, Aya, Tsukamoto, Kiyoshi, Matsubara, Nagahide, Tomita, Naohiro

Journal:

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015